Basic Information
ID: ALA4146981
Type: Functional
Description: Antagonist activity at rat GnRH receptor expressed in HEK293 cells co-expressing pGL4-NFATpromoter AP-1-luc assessed as inhibition of GnRH-induced NFAT promoter activation preincubated for 1 hr followed by GnRH addition measured after 6 hrs by luciferase reporter gene assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4146981
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 577.63 | 4.82 | 4.82 |
| 721.70 | 5.22 | 5.22 |
| 685.72 | 4.94 | 4.94 |