Basic Information
ID: ALA4147359
Type: Binding
Description: Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylation using [methyl-3H]AdoMet measured after 1 hr
Organism: Bacteria
Activity Charts
Bioactivity
Activity Types for Assay ALA4147359
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.39 | 2.22 | 2.22 |
| 346.44 | 3.98 | 3.98 |
| 324.41 | 2.79 | 2.79 |
| 332.39 | 4.01 | 4.01 |
| 295.32 | 3.40 | 3.40 |
| 322.34 | 4.07 | 4.07 |
| 326.28 | 1.18 | 1.18 |
| 325.29 | 1.79 | 1.79 |
| 292.32 | 1.46 | 1.46 |
| 337.81 | 4.60 | 4.60 |
| 387.41 | 3.81 | 3.81 |
| 393.20 | 3.70 | 3.70 |
| 338.44 | 3.09 | 3.09 |
| 317.33 | 1.08 | 1.08 |
| 336.35 | 2.77 | 2.77 |
| 311.27 | 1.73 | 1.73 |
| 335.34 | 3.73 | 3.73 |
| 336.40 | 3.59 | 3.59 |
| 310.33 | 2.80 | 2.80 |
| 448.47 | 3.97 | 3.97 |
| 325.29 | 2.04 | 2.04 |
| 343.34 | 3.44 | 3.44 |
| 341.42 | 2.11 | 2.11 |
| 402.38 | 2.64 | 2.64 |
| 340.41 | 2.70 | 2.70 |
| 331.38 | 3.61 | 3.61 |
| 361.37 | 3.07 | 3.07 |
| 336.38 | 2.63 | 2.63 |
| 353.39 | 2.87 | 2.87 |
| 341.29 | 1.08 | 1.08 |
| 365.36 | 2.66 | 2.66 |
| 325.29 | 2.04 | 2.04 |
| 341.39 | 3.48 | 3.48 |
| 321.38 | 2.26 | 2.26 |
| 334.36 | 0.05 | 0.05 |
| 366.34 | 2.59 | 2.59 |
| 341.33 | 1.56 | 1.56 |
| 346.39 | 3.60 | 3.60 |
| 311.27 | 1.73 | 1.73 |
| 346.75 | 3.36 | 3.36 |
| 291.36 | 2.15 | 2.15 |
| 319.39 | 1.56 | 1.56 |
| 346.45 | 1.79 | 1.79 |
| 342.28 | 0.47 | 0.47 |
| 435.44 | 3.05 | 3.05 |