Assay Report Card

Basic Information

ID: ALA4148151

Type: Binding

Description: Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 10 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control

Organism: Mus musculus

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
314.362.682.68
322.364.074.07
390.365.095.09
378.475.375.37
340.354.214.21
336.394.384.38
352.394.084.08
367.363.983.98