Basic Information
ID: ALA4148153
Type: Binding
Description: Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 5 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: Cyclooxygenase-2(ALA4321)
Document: ALA4145523
Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 5 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4148153
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.36 | 2.68 | 2.68 |
| 352.39 | 4.08 | 4.08 |