Basic Information
ID: ALA4148161
Type: Functional
Description: Antiplasmodial activity against erythrocytic stage of Plasmodium falciparum NF54 assessed as reduction in [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting method
Format: BAO_0000218
Organism: Plasmodium falciparum
Strain: NF54
Target: Plasmodium falciparum(ALA364)
Document: ALA4145525
Antiplasmodial activity against erythrocytic stage of Plasmodium falciparum NF54 assessed as reduction in [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4148161
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.34 | 2.78 | 2.78 |
| 393.49 | 3.72 | 3.72 |
| 370.50 | 4.07 | 4.07 |
| 384.52 | 4.46 | 4.46 |
| 466.67 | 6.50 | 6.50 |
| 360.46 | 2.51 | 2.51 |
| 346.43 | 2.12 | 2.12 |
| 544.70 | 5.96 | 5.96 |
| 419.53 | 4.66 | 4.66 |
| 389.50 | 4.65 | 4.65 |
| 423.94 | 5.31 | 5.31 |
| 540.67 | 5.47 | 5.47 |
| 561.09 | 5.78 | 5.78 |
| 569.67 | 4.80 | 4.80 |
| 599.69 | 4.81 | 4.81 |
| 645.81 | 5.92 | 5.92 |
| 602.74 | 5.18 | 5.18 |
| 538.96 | 5.53 | 5.53 |
| 418.50 | 1.72 | 1.72 |
| 446.55 | 2.50 | 2.50 |
| 448.52 | 1.03 | 1.03 |
| 464.52 | 0.05 | 0.05 |
| 503.05 | 6.57 | 6.57 |
| 511.63 | 5.58 | 5.58 |
| 541.65 | 5.59 | 5.59 |
| 587.77 | 6.70 | 6.70 |
| 480.92 | 6.32 | 6.32 |
| 514.47 | 6.68 | 6.68 |
| 504.51 | 4.88 | 4.88 |
| 470.96 | 4.51 | 4.51 |
| 470.96 | 4.51 | 4.51 |
| 504.51 | 4.88 | 4.88 |
| 515.41 | 4.62 | 4.62 |
| 537.62 | 3.89 | 3.89 |
| 525.49 | 6.69 | 6.69 |
| 636.20 | 7.42 | 7.42 |
| 449.55 | 4.67 | 4.67 |
| 515.54 | 4.89 | 4.89 |
| 464.57 | 3.58 | 3.58 |
| 461.57 | 4.26 | 4.26 |
| 679.22 | 7.10 | 7.10 |
| 403.53 | 5.04 | 5.04 |
| 583.53 | 5.91 | 5.91 |
| 457.50 | 5.67 | 5.67 |
| 491.55 | 3.60 | 3.60 |
| 526.64 | 5.13 | 5.13 |
| 447.54 | 3.87 | 3.87 |
| 581.76 | 6.44 | 6.44 |
| 507.59 | 3.89 | 3.89 |
| 466.54 | 3.47 | 3.47 |
| 428.54 | 3.28 | 3.28 |
| 636.20 | 7.42 | 7.42 |
| 450.54 | 3.54 | 3.54 |
| 457.50 | 5.67 | 5.67 |
| 670.64 | 8.08 | 8.08 |
| 479.58 | 4.68 | 4.68 |
| 465.53 | 4.01 | 4.01 |
| 407.49 | 4.79 | 4.79 |
| 477.57 | 3.88 | 3.88 |
| 615.78 | 7.11 | 7.11 |
| 433.51 | 4.38 | 4.38 |
| 442.56 | 3.67 | 3.67 |
| 624.97 | 6.92 | 6.92 |
| 515.54 | 4.89 | 4.89 |
| 481.98 | 4.52 | 4.52 |