Basic Information
ID: ALA4148665
Type: Binding
Description: Inhibition of biotinylated-H4KAc4 binding to human His6-tagged CBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by luminescence-based AlphaScreen assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CREB-binding protein(ALA5747)
Document: ALA4145544
Inhibition of biotinylated-H4KAc4 binding to human His6-tagged CBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by luminescence-based AlphaScreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4148665
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 3.31 | 3.31 |
| 266.30 | 3.41 | 3.41 |
| 226.23 | 3.49 | 3.49 |
| 252.27 | 3.12 | 3.12 |
| 230.27 | 1.98 | 1.98 |
| 242.28 | 2.59 | 2.59 |
| 509.05 | 5.48 | 5.48 |
| 388.38 | 4.51 | 4.51 |
| 231.25 | 2.32 | 2.32 |
| 446.46 | 5.30 | 5.30 |
| 336.35 | 3.34 | 3.34 |
| 266.26 | 2.95 | 2.95 |
| 416.41 | 5.06 | 5.06 |
| 393.44 | 4.46 | 4.46 |
| 328.37 | 2.17 | 2.17 |
| 401.22 | 4.01 | 4.01 |
| 404.47 | 5.30 | 5.30 |
| 240.31 | 2.95 | 2.95 |
| 379.42 | 4.07 | 4.07 |
| 486.48 | 4.70 | 4.70 |
| 438.44 | 5.67 | 5.67 |
| 432.44 | 3.66 | 3.66 |
| 377.40 | 3.83 | 3.83 |
| 314.35 | 1.06 | 1.06 |
| 270.72 | 3.25 | 3.25 |
| 421.45 | 3.84 | 3.84 |
| 362.39 | 4.13 | 4.13 |
| 435.48 | 4.09 | 4.09 |
| 404.38 | 4.22 | 4.22 |
| 250.17 | 1.51 | 1.51 |
| 398.42 | 4.92 | 4.92 |
| 413.43 | 4.62 | 4.62 |
| 231.25 | 2.36 | 2.36 |
| 428.44 | 4.93 | 4.93 |
| 320.35 | 3.76 | 3.76 |
| 433.51 | 5.24 | 5.24 |
| 342.40 | 2.26 | 2.26 |
| 185.19 | 1.57 | 1.57 |
| 350.37 | 3.81 | 3.81 |
| 436.46 | 4.30 | 4.30 |
| 259.30 | 2.80 | 2.80 |
| 432.43 | 4.91 | 4.91 |
| 432.86 | 5.57 | 5.57 |
| 393.44 | 4.32 | 4.32 |
| 450.43 | 3.80 | 3.80 |
| 328.37 | 2.17 | 2.17 |
| 340.31 | 3.39 | 3.39 |
| 433.51 | 5.39 | 5.39 |
| 322.32 | 3.25 | 3.25 |
| 390.44 | 4.91 | 4.91 |
| 418.41 | 4.52 | 4.52 |
| 482.50 | 4.81 | 4.81 |
| 452.47 | 4.81 | 4.81 |
| 405.45 | 4.61 | 4.61 |
| 287.32 | 1.17 | 1.17 |
| 466.42 | 5.94 | 5.94 |
| 391.43 | 4.07 | 4.07 |
| 342.40 | 2.26 | 2.26 |
| 427.46 | 4.86 | 4.86 |
| 378.43 | 4.45 | 4.45 |
| 426.47 | 5.04 | 5.04 |