Basic Information
ID: ALA4148666
Type: Binding
Description: Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) at 50 uM after 2.5 hrs by luminescence-based AlphaScreen assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4145544
Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) at 50 uM after 2.5 hrs by luminescence-based AlphaScreen assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4148666
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 3.31 | 3.31 |
| 266.30 | 3.41 | 3.41 |
| 226.23 | 3.49 | 3.49 |
| 252.27 | 3.12 | 3.12 |
| 230.27 | 1.98 | 1.98 |
| 242.28 | 2.59 | 2.59 |
| 509.05 | 5.48 | 5.48 |
| 231.25 | 2.32 | 2.32 |
| 266.26 | 2.95 | 2.95 |
| 240.31 | 2.95 | 2.95 |
| 270.72 | 3.25 | 3.25 |
| 250.17 | 1.51 | 1.51 |
| 231.25 | 2.36 | 2.36 |
| 185.19 | 1.57 | 1.57 |