Basic Information
ID: ALA4148788
Type: Binding
Description: Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Spleen
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4148788
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.97 | 4.66 | 4.66 |
| 292.77 | 2.91 | 2.91 |
| 264.33 | 3.28 | 3.28 |
| 306.79 | 3.30 | 3.30 |
| 483.94 | 5.49 | 5.49 |
| 280.33 | 3.41 | 3.41 |
| 264.33 | 3.28 | 3.28 |
| 258.32 | 2.26 | 2.26 |
| 215.26 | 1.48 | 1.48 |
| 309.21 | 3.89 | 3.89 |
| 356.21 | 3.74 | 3.74 |
| 323.87 | 4.72 | 4.72 |
| 337.90 | 5.11 | 5.11 |
| 294.35 | 3.20 | 3.20 |
| 343.22 | 4.05 | 4.05 |
| 278.36 | 3.21 | 3.21 |
| 373.25 | 3.96 | 3.96 |
| 290.37 | 3.67 | 3.67 |
| 314.13 | 2.22 | 2.22 |
| 298.77 | 3.94 | 3.94 |
| 420.25 | 3.80 | 3.80 |
| 245.33 | 2.06 | 2.06 |
| 328.80 | 3.85 | 3.85 |
| 234.73 | 3.56 | 3.56 |
| 267.13 | 2.38 | 2.38 |