Basic Information
ID: ALA4149970
Type: Binding
Description: Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorescein probe based spectrofluorimetric thioesterolysis assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Complement factor D(ALA2176771)
Document: ALA4145599
Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorescein probe based spectrofluorimetric thioesterolysis assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4149970
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.43 | 3.68 | 3.68 |
| 302.38 | 4.06 | 4.06 |
| 356.47 | 4.62 | 4.62 |
| 356.47 | 4.62 | 4.62 |
| 391.48 | 3.89 | 3.89 |
| 316.40 | 3.74 | 3.74 |
| 316.40 | 3.99 | 3.99 |
| 365.44 | 3.35 | 3.35 |
| 282.39 | 3.80 | 3.80 |
| 455.60 | 5.60 | 5.60 |
| 315.38 | 2.20 | 2.20 |
| 240.31 | 2.77 | 2.77 |
| 330.43 | 4.38 | 4.38 |
| 347.38 | 3.00 | 3.00 |