Inhibition of human partial length PIK3CA E545K mutant (R108 to N1068 residues) expressed in mammalian expression system assessed as residual activity...

Basic Information

ID: ALA4150405

Type: Binding

Description: Inhibition of human partial length PIK3CA E545K mutant (R108 to N1068 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control

Format: BAO_0000019

Organism: Homo sapiens

Target:  PI3-kinase p110-alpha subunit(ALA4005)

Document:  ALA4145625

Inhibition of human partial length PIK3CA E545K mutant (R108 to N1068 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
557.584.234.23