Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of N-((3S,17S)-17-(isoquinolin-7-yl)-10,13-...

ID: ALA4150541

Type: Binding

Description: Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of N-((3S,17S)-17-(isoquinolin-7-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)-Nmethyl-1-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-amide by immunoblot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Jurkat

Target:  Cereblon/Cyclin-dependent kinase 8(ALA4296125)

Document:  ALA4145630

Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of N-((3S,17S)-17-(isoquinolin-7-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)-Nmethyl-1-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-amide by immunoblot analysis: 1