Basic Information
ID: ALA4150561
Type: Binding
Description: Inhibition of NOTUM in human SW620 cells conditioned medium assessed as preservation of Wnt3A activity pretreated for 1 hr followed by Wnt3A producing L-cell addition for 2 hrs and subsequent HEK393-STF cell addition and measured after 24 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)
Document: ALA4145632
Inhibition of NOTUM in human SW620 cells conditioned medium assessed as preservation of Wnt3A activity pretreated for 1 hr followed by Wnt3A producing L-cell addition for 2 hrs and subsequent HEK393-STF cell addition and measured after 24 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4150561
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.87 | 2.38 | 2.38 |
| 456.89 | 2.74 | 2.74 |