Basic Information
ID: ALA4150763
Type: Binding
Description: Inhibition of Net1 (149 to 501 residues) (unknown origin) interaction with GDP-loaded His-tagged RhoA F25N mutant (1 to 180 residues) assessed as reduction in BODIPY-GTP-GDP exchange at 200 uM pretreated for 30 mins followed by RhoA addition by fluorescence based spectrophotometric method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4150763
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.31 | 2.32 | 2.32 |
| 293.28 | 2.84 | 2.84 |
| 272.39 | 4.33 | 4.33 |
| 277.32 | 3.71 | 3.71 |
| 330.29 | 3.04 | 3.04 |
| 310.44 | 4.73 | 4.73 |
| 398.54 | 5.13 | 5.13 |
| 281.27 | 2.98 | 2.98 |
| 370.49 | 4.35 | 4.35 |
| 370.49 | 4.35 | 4.35 |