Basic Information
ID: ALA4150967
Type: Binding
Description: Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4150967
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 133.10 | -1.13 | -1.13 |
| 239.23 | 0.07 | 0.07 |
| 147.13 | -0.74 | -0.74 |
| 149.10 | -2.16 | -2.16 |
| 426.35 | 2.34 | 2.34 |
| 415.19 | 3.26 | 3.26 |
| 203.19 | -0.72 | -0.72 |
| 203.19 | -0.72 | -0.72 |
| 426.35 | 2.34 | 2.34 |
| 245.26 | 0.13 | 0.13 |
| 259.30 | 0.84 | 0.84 |
| 245.27 | 0.45 | 0.45 |
| 231.25 | 0.06 | 0.06 |
| 440.37 | 2.27 | 2.27 |
| 188.14 | -1.61 | -1.61 |
| 229.19 | -0.34 | -0.34 |
| 187.15 | -1.50 | -1.50 |
| 188.14 | -1.61 | -1.61 |
| 245.26 | 0.13 | 0.13 |
| 426.35 | 2.34 | 2.34 |
| 217.22 | -0.33 | -0.33 |
| 454.40 | 2.66 | 2.66 |
| 521.31 | 4.46 | 4.46 |
| 245.26 | 0.13 | 0.13 |
| 229.19 | -0.34 | -0.34 |
| 402.45 | 3.19 | 3.19 |