Basic Information
ID: ALA4150974
Type: Binding
Description: Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM pre-incubated before L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4150974
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 203.19 | -0.72 | -0.72 |
| 245.26 | 0.13 | 0.13 |
| 259.30 | 0.84 | 0.84 |
| 245.27 | 0.45 | 0.45 |
| 231.25 | 0.06 | 0.06 |
| 229.19 | -0.34 | -0.34 |
| 187.15 | -1.50 | -1.50 |
| 245.26 | 0.13 | 0.13 |
| 217.22 | -0.33 | -0.33 |
| 229.19 | -0.34 | -0.34 |