Basic Information
ID: ALA4151113
Type: Binding
Description: Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substrate addition and measured after 60 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4151113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.40 | 2.38 | 2.38 |
| 322.36 | 3.06 | 3.06 |
| 310.31 | 2.19 | 2.19 |
| 374.34 | 3.35 | 3.35 |
| 338.36 | 2.76 | 2.76 |
| 258.28 | 1.59 | 1.59 |
| 236.27 | 2.73 | 2.73 |
| 326.33 | 2.89 | 2.89 |
| 338.36 | 2.24 | 2.24 |
| 307.35 | 2.15 | 2.15 |
| 314.37 | 2.81 | 2.81 |
| 280.28 | 2.43 | 2.43 |
| 322.36 | 3.06 | 3.06 |
| 337.34 | 1.54 | 1.54 |
| 306.32 | 2.83 | 2.83 |
| 309.32 | 2.14 | 2.14 |
| 304.27 | 3.75 | 3.75 |
| 322.36 | 3.06 | 3.06 |
| 392.33 | 3.65 | 3.65 |
| 322.36 | 3.06 | 3.06 |
| 385.45 | 1.74 | 1.74 |
| 342.78 | 3.40 | 3.40 |
| 314.37 | 2.81 | 2.81 |
| 348.40 | 3.62 | 3.62 |
| 333.35 | 2.62 | 2.62 |
| 294.31 | 2.49 | 2.49 |
| 406.36 | 3.69 | 3.69 |
| 336.39 | 3.31 | 3.31 |
| 308.34 | 2.75 | 2.75 |
| 311.34 | 1.40 | 1.40 |
| 376.33 | 3.77 | 3.77 |
| 294.31 | 2.36 | 2.36 |