Basic Information
ID: ALA4151410
Type: Functional
Description: Potency index, ratio of pA2 for test compound to pA2 for AGRP for antagonist activity at mouse MC4R expressed in HEK293 cells assessed as reduction in NDP-MSH-induced response incubated for 2 hrs by AlphaScreen cAMP assay based Schild analysis
Format: BAO_0000219
Organism: Mus musculus
Target: Melanocortin receptor 4(ALA3719)
Document: ALA4145669
Potency index, ratio of pA2 for test compound to pA2 for AGRP for antagonist activity at mouse MC4R expressed in HEK293 cells assessed as reduction in NDP-MSH-induced response incubated for 2 hrs by AlphaScreen cAMP assay based Schild analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4151410
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 945.14 | -1.83 | -1.83 |
| 973.15 | -1.91 | -1.91 |