Basic Information
ID: ALA4151497
Type: Binding
Description: Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cells assessed as reduction in ATP-dependent ULight-4E-BP1 (Thr37/Thr46) substrate peptide phosphorylation pre-incubated for 60 mins by LANCE Ultra assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Cyclin-dependent kinase 13/Cyclin-K(ALA4296067)
Document: ALA4145674
Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cells assessed as reduction in ATP-dependent ULight-4E-BP1 (Thr37/Thr46) substrate peptide phosphorylation pre-incubated for 60 mins by LANCE Ultra assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4151497
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 532.65 | 5.46 | 5.46 |
| 505.63 | 5.49 | 5.49 |