Basic Information
ID: ALA4151514
Type: Binding
Description: Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as minimal potentiating drug concentration causing 8 fold reduction in ciprofloxacin MIC by microdilution method based Checkerboard assay
Organism: Staphylococcus aureus
Strain: SA-1199B
Activity Charts
Bioactivity
Activity Types for Assay ALA4151514
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 608.69 | 4.17 | 4.17 |
| 378.52 | 5.41 | 5.41 |
| 464.61 | 5.96 | 5.96 |
| 420.55 | 5.56 | 5.56 |
| 434.58 | 5.95 | 5.95 |
| 420.55 | 5.56 | 5.56 |
| 420.55 | 5.56 | 5.56 |
| 309.37 | 4.40 | 4.40 |
| 335.40 | 5.22 | 5.22 |
| 438.57 | 5.43 | 5.43 |
| 450.58 | 5.57 | 5.57 |
| 408.54 | 5.42 | 5.42 |
| 408.54 | 5.42 | 5.42 |
| 528.65 | 6.15 | 6.15 |
| 371.86 | 5.32 | 5.32 |
| 528.65 | 6.15 | 6.15 |
| 339.39 | 4.41 | 4.41 |
| 434.58 | 5.95 | 5.95 |
| 511.67 | 5.90 | 5.90 |
| 438.57 | 5.43 | 5.43 |
| 511.67 | 5.90 | 5.90 |
| 408.54 | 5.42 | 5.42 |
| 450.58 | 5.57 | 5.57 |
| 420.55 | 5.56 | 5.56 |
| 434.58 | 5.95 | 5.95 |
| 558.68 | 6.16 | 6.16 |
| 558.68 | 6.16 | 6.16 |
| 450.58 | 5.57 | 5.57 |
| 421.54 | 3.98 | 3.98 |
| 464.61 | 5.96 | 5.96 |
| 464.61 | 5.96 | 5.96 |
| 408.54 | 5.42 | 5.42 |
| 434.58 | 5.95 | 5.95 |
| 421.54 | 3.98 | 3.98 |
| 394.52 | 5.03 | 5.03 |
| 371.86 | 5.32 | 5.32 |
| 309.37 | 4.40 | 4.40 |
| 528.65 | 6.15 | 6.15 |
| 558.68 | 6.16 | 6.16 |
| 438.57 | 5.43 | 5.43 |
| 394.52 | 5.03 | 5.03 |
| 394.52 | 5.03 | 5.03 |
| 421.54 | 3.98 | 3.98 |
| 371.86 | 5.32 | 5.32 |