Basic Information
ID: ALA4151582
Type: Binding
Description: Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4151582
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.58 | 3.64 | 3.64 |
| 297.36 | 5.04 | 5.04 |
| 357.41 | 5.06 | 5.06 |
| 342.36 | 4.95 | 4.95 |
| 368.36 | 4.22 | 4.22 |
| 456.45 | 6.69 | 6.69 |
| 372.38 | 4.96 | 4.96 |
| 492.50 | 5.60 | 5.60 |
| 374.36 | 4.36 | 4.36 |
| 403.35 | 4.56 | 4.56 |
| 397.39 | 4.83 | 4.83 |
| 367.37 | 4.82 | 4.82 |
| 373.37 | 4.35 | 4.35 |
| 410.36 | 5.97 | 5.97 |
| 428.35 | 6.11 | 6.11 |
| 470.41 | 5.98 | 5.98 |
| 427.46 | 5.06 | 5.06 |
| 380.37 | 5.64 | 5.64 |
| 386.37 | 4.65 | 4.65 |
| 471.35 | 5.58 | 5.58 |
| 410.40 | 5.65 | 5.65 |
| 410.36 | 5.97 | 5.97 |
| 470.41 | 5.98 | 5.98 |
| 426.35 | 5.67 | 5.67 |
| 343.39 | 4.03 | 4.03 |
| 358.36 | 4.65 | 4.65 |
| 399.41 | 4.91 | 4.91 |
| 402.41 | 4.97 | 4.97 |
| 448.49 | 5.09 | 5.09 |
| 467.41 | 5.93 | 5.93 |
| 360.35 | 5.09 | 5.09 |
| 492.50 | 5.60 | 5.60 |
| 390.37 | 5.10 | 5.10 |
| 396.37 | 5.35 | 5.35 |
| 373.37 | 4.35 | 4.35 |
| 367.37 | 4.82 | 4.82 |
| 455.35 | 5.88 | 5.88 |
| 373.37 | 4.35 | 4.35 |
| 455.35 | 5.88 | 5.88 |
| 440.38 | 5.98 | 5.98 |
| 343.39 | 4.03 | 4.03 |