Basic Information
ID: ALA4151587
Type: Toxicity
Description: Therapeutic index, ratio of GI50 for intrinsic cytotoxicity in MDCK2 cells overexpressing BCRP to IC50 for inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells
Activity Charts
Bioactivity
Activity Types for Assay ALA4151587
TI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.58 | 3.64 | 3.64 |
| 297.36 | 5.04 | 5.04 |
| 357.41 | 5.06 | 5.06 |
| 342.36 | 4.95 | 4.95 |
| 368.36 | 4.22 | 4.22 |
| 372.38 | 4.96 | 4.96 |
| 403.35 | 4.56 | 4.56 |
| 397.39 | 4.83 | 4.83 |
| 373.37 | 4.35 | 4.35 |
| 471.35 | 5.58 | 5.58 |
| 470.41 | 5.98 | 5.98 |
| 426.35 | 5.67 | 5.67 |
| 402.41 | 4.97 | 4.97 |
| 390.37 | 5.10 | 5.10 |
| 343.39 | 4.03 | 4.03 |