Basic Information
ID: ALA4151790
Type: Binding
Description: Antagonist activity at human GR expressed in CHO-K1 cells assessed as reduction in dexamethasone-induced response incubated for 20 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4151790
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.60 | 5.41 | 5.41 |
| 386.54 | 5.34 | 5.34 |
| 443.63 | 5.80 | 5.80 |
| 473.70 | 6.37 | 6.37 |
| 458.64 | 6.38 | 6.38 |
| 485.71 | 6.74 | 6.74 |
| 501.76 | 7.15 | 7.15 |
| 429.60 | 5.41 | 5.41 |
| 497.72 | 6.97 | 6.97 |
| 471.69 | 6.43 | 6.43 |
| 483.57 | 5.95 | 5.95 |
| 507.67 | 6.71 | 6.71 |
| 499.74 | 7.21 | 7.21 |
| 456.67 | 6.93 | 6.93 |
| 392.58 | 5.75 | 5.75 |
| 457.66 | 6.04 | 6.04 |
| 498.71 | 6.65 | 6.65 |
| 471.69 | 6.43 | 6.43 |
| 501.71 | 6.44 | 6.44 |
| 489.70 | 5.75 | 5.75 |
| 442.64 | 6.68 | 6.68 |
| 513.72 | 6.20 | 6.20 |
| 428.62 | 6.46 | 6.46 |
| 507.67 | 6.71 | 6.71 |
| 561.79 | 5.60 | 5.60 |
| 470.70 | 7.49 | 7.49 |
| 338.49 | 4.58 | 4.58 |
| 447.66 | 6.57 | 6.57 |