Basic Information
ID: ALA4151850
Type: Functional
Description: In-vivo antagonist activity at GR in nude mouse xenografted with human OVCAR5 cells assessed as reduction in dexamethasone-induced FKBP5 gene expression at 25 to 75 mg/kg, po dosed as gavage and measured after 6 hrs by RT-qPCR method
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4151850
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.76 | 7.15 | 7.15 |