Assay Report Card

Basic Information

ID: ALA4151854

Type: Functional

Description: Potentiation of gemcitabine-induced antitumor activity against human OVCAR5 cells xenografted in chronic cortisol treated nude mouse assessed as reduction in tumor volume at 75 mg/kg, po BID dosed via gavage co-treated with gencitabine at 100 mg/kg dosed every 3 days for 4 doses

Organism: Homo sapiens

Cell type: OVCAR-5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
501.767.157.15