Basic Information
ID: ALA4151994
Type: Binding
Description: Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes pre-incubated for 1 hr by FRET-based binding assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4151994
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.31 | 3.31 | 3.31 |
| 288.73 | 3.95 | 3.95 |
| 274.70 | 3.65 | 3.65 |
| 272.73 | 4.24 | 4.24 |
| 302.76 | 4.25 | 4.25 |
| 258.70 | 3.94 | 3.94 |
| 288.73 | 3.95 | 3.95 |
| 322.28 | 4.32 | 4.32 |
| 254.28 | 3.30 | 3.30 |
| 302.71 | 3.64 | 3.64 |
| 442.34 | 3.31 | 3.31 |
| 300.74 | 4.01 | 4.01 |
| 333.18 | 4.06 | 4.06 |
| 323.17 | 4.60 | 4.60 |
| 302.71 | 3.67 | 3.67 |
| 255.27 | 2.69 | 2.69 |
| 344.80 | 3.75 | 3.75 |
| 316.74 | 3.71 | 3.71 |
| 302.76 | 4.34 | 4.34 |
| 300.74 | 3.88 | 3.88 |
| 326.78 | 4.49 | 4.49 |
| 341.80 | 4.22 | 4.22 |
| 323.17 | 4.60 | 4.60 |
| 290.75 | 3.87 | 3.87 |
| 288.73 | 3.95 | 3.95 |
| 328.76 | 3.47 | 3.47 |
| 398.29 | 3.30 | 3.30 |
| 323.17 | 4.60 | 4.60 |
| 380.18 | 3.90 | 3.90 |
| 306.72 | 4.09 | 4.09 |
| 255.27 | 2.69 | 2.69 |
| 302.76 | 3.49 | 3.49 |
| 272.27 | 3.44 | 3.44 |
| 296.37 | 4.42 | 4.42 |
| 288.73 | 3.95 | 3.95 |
| 323.17 | 4.60 | 4.60 |
| 317.73 | 4.15 | 4.15 |
| 268.31 | 3.61 | 3.61 |
| 287.75 | 3.83 | 3.83 |
| 302.76 | 4.34 | 4.34 |
| 300.75 | 4.11 | 4.11 |
| 327.77 | 3.76 | 3.76 |
| 410.30 | 3.22 | 3.22 |
| 354.23 | 3.28 | 3.28 |
| 323.17 | 4.60 | 4.60 |
| 298.29 | 3.00 | 3.00 |
| 303.75 | 3.95 | 3.95 |