Basic Information
ID: ALA4152411
Type: Binding
Description: Inhibition of mmLDL-stimulated acid sphingomyelinase in human PBMC lysates using 3H-sphingomyelin as substrate preincubated for 30 mins followed by mmLDL stimulation measured after 2 hrs by HPLC method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4152411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.42 | 3.88 | 3.88 |
| 318.87 | 4.89 | 4.89 |
| 269.30 | 2.62 | 2.62 |
| 282.30 | 1.75 | 1.75 |
| 390.55 | 5.47 | 5.47 |
| 402.54 | 5.38 | 5.38 |
| 439.02 | 6.52 | 6.52 |
| 386.54 | 5.11 | 5.11 |
| 404.55 | 5.41 | 5.41 |
| 530.46 | 7.39 | 7.39 |
| 418.54 | 5.51 | 5.51 |
| 442.60 | 5.10 | 5.10 |
| 402.45 | 3.28 | 3.28 |
| 404.58 | 5.86 | 5.86 |
| 386.50 | 4.89 | 4.89 |
| 321.42 | 4.19 | 4.19 |
| 354.45 | 2.99 | 2.99 |
| 414.55 | 5.02 | 5.02 |
| 455.65 | 5.83 | 5.83 |
| 400.52 | 4.63 | 4.63 |
| 322.45 | 4.21 | 4.21 |
| 430.59 | 4.70 | 4.70 |
| 388.51 | 5.50 | 5.50 |
| 372.51 | 5.37 | 5.37 |
| 397.56 | 5.79 | 5.79 |
| 287.36 | 4.85 | 4.85 |
| 416.57 | 5.12 | 5.12 |
| 427.59 | 5.80 | 5.80 |
| 666.91 | 9.05 | 9.05 |
| 360.50 | 4.98 | 4.98 |
| 471.65 | 5.97 | 5.97 |
| 485.67 | 5.84 | 5.84 |
| 455.02 | 6.13 | 6.13 |
| 414.59 | 5.37 | 5.37 |
| 374.53 | 5.40 | 5.40 |
| 358.49 | 5.33 | 5.33 |
| 350.46 | 4.10 | 4.10 |
| 400.57 | 5.50 | 5.50 |
| 413.57 | 4.66 | 4.66 |
| 430.59 | 5.51 | 5.51 |
| 434.61 | 5.87 | 5.87 |
| 320.44 | 4.09 | 4.09 |
| 318.42 | 4.34 | 4.34 |
| 469.05 | 6.52 | 6.52 |
| 291.39 | 4.18 | 4.18 |
| 412.58 | 5.09 | 5.09 |
| 346.47 | 4.59 | 4.59 |
| 483.03 | 6.05 | 6.05 |
| 400.57 | 4.70 | 4.70 |
| 358.49 | 4.98 | 4.98 |