Basic Information
ID: ALA4152844
Type: Binding
Description: Induction of CRL4/CRBN ubiquitin ligase-mediated EML4-ALK fusion protein degradation in human NCI-H2228 cells assessed as reduction in EML4-ALK fusion protein levels at 100 nM after 16 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H2228
Activity Charts
Bioactivity
Activity Types for Assay ALA4152844
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.15 | 6.36 | 6.36 |
| 1148.78 | ||
| 914.49 | 5.70 | 5.70 |
| 1134.75 | ||
| 928.51 | 6.05 | 6.05 |