ID: ALA4152845
Type: Binding
Description: Induction of CRL4/CRBN ubiquitin ligase-mediated EML4-ALK fusion protein degradation in human SU-DHL1 cells assessed as reduction in ALK autophosphorylation at Y1507 residue at 30 nM after 2 hrs by Western blot analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4152845
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
914.49 | 5.70 | 5.70 |
1134.75 |