Assay Report Card

Basic Information

ID: ALA4152845

Type: Binding

Description: Induction of CRL4/CRBN ubiquitin ligase-mediated EML4-ALK fusion protein degradation in human SU-DHL1 cells assessed as reduction in ALK autophosphorylation at Y1507 residue at 30 nM after 2 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
914.495.705.70
1134.75