Basic Information
ID: ALA4152849
Type: Binding
Description: Induction of CRL4/CRBN ubiquitin ligase-mediated EML4-ALK fusion protein degradation assessed as inhibition of ALK autophosphorylation at Y1507 residue in human NCI-H2228 cells at 60 nM after 8 to 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H2228
Activity Charts
Bioactivity
Activity Types for Assay ALA4152849
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 914.49 | 5.70 | 5.70 |
| 1134.75 |