Assay Report Card

Basic Information

ID: ALA4152852

Type: Binding

Description: Induction of CRL4/CRBN ubiquitin ligase-mediated NPM-ALK fusion protein degradation in human SU-DHL1 cells pretreated with pomalidomide for 2 hrs followed by compound addition at 100 nM and measured after 6 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
914.495.705.70
1134.75