Basic Information
ID: ALA4152858
Type: Binding
Description: Induction of CRL4/CRBN ubiquitin ligase-mediated NPM-ALK fusion protein degradation in human SU-DHL1 cells assessed as inhibition of ALK autophosphorylation at Y1507 residue pretreated at 100 nM for 2 hrs followed by compound washout and measured after 8 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4152858
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 914.49 | 5.70 | 5.70 |
| 1134.75 |