Basic Information
ID: ALA4152867
Type: Binding
Description: Induction of CRL4/CRBN ubiquitin ligase-mediated EML4-ALK fusion protein degradation in human NCI-H2228 cells assessed as reduction in STAT3 phosphorylation at Y705 residue at 60 nM after 8 to 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H2228
Activity Charts
Bioactivity
Activity Types for Assay ALA4152867
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 914.49 | 5.70 | 5.70 |
| 1134.75 |