Basic Information
ID: ALA4153026
Type: Binding
Description: Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4153026
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.36 | 2.96 | 2.96 |
| 360.36 | 2.96 | 2.96 |
| 410.47 | 5.09 | 5.09 |
| 478.59 | 6.82 | 6.82 |
| 516.40 | -0.27 | -0.27 |
| 488.34 | -1.05 | -1.05 |
| 468.46 | 2.05 | 2.05 |
| 480.54 | 3.80 | 3.80 |
| 434.91 | 1.69 | 1.69 |
| 468.45 | 4.03 | 4.03 |
| 512.47 | 5.51 | 5.51 |
| 560.03 | 3.99 | 3.99 |
| 477.90 | 4.97 | 4.97 |
| 322.16 | 3.15 | 3.15 |
| 414.50 | 5.25 | 5.25 |
| 420.09 | -3.48 | -3.48 |
| 424.49 | 5.39 | 5.39 |
| 273.29 | 2.39 | 2.39 |
| 273.29 | 2.39 | 2.39 |
| 309.41 | 4.03 | 4.03 |
| 645.32 | 6.94 | 6.94 |
| 427.45 | 3.34 | 3.34 |
| 295.38 | 3.55 | 3.55 |
| 268.27 | 2.26 | 2.26 |
| 334.24 | 2.67 | 2.67 |
| 344.37 | 4.77 | 4.77 |
| 349.26 | 1.96 | 1.96 |
| 351.49 | 3.94 | 3.94 |
| 377.31 | 2.74 | 2.74 |
| 293.41 | 4.33 | 4.33 |
| 402.28 | 4.32 | 4.32 |
| 323.43 | 4.33 | 4.33 |
| 243.26 | 2.38 | 2.38 |
| 399.40 | 2.61 | 2.61 |
| 306.19 | 1.89 | 1.89 |
| 352.18 | 3.16 | 3.16 |
| 322.40 | 4.16 | 4.16 |
| 321.46 | 5.11 | 5.11 |
| 330.39 | 3.67 | 3.67 |
| 348.27 | 3.06 | 3.06 |
| 558.48 | 1.25 | 1.25 |
| 265.35 | 3.54 | 3.54 |
| 341.31 | 4.26 | 4.26 |
| 351.49 | 5.11 | 5.11 |
| 418.24 | 4.07 | 4.07 |
| 365.51 | 4.33 | 4.33 |
| 505.93 | 5.01 | 5.01 |
| 378.30 | 2.77 | 2.77 |