Basic Information
ID: ALA4153627
Type: Binding
Description: Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by biotin tagged H3 peptide ( 1 to 23 residues) and [3H]-Ac-CoA addition and measured after 60 mins by radioactive acetylation assay
Organism: Saccharomyces cerevisiae
Activity Charts
Bioactivity
Activity Types for Assay ALA4153627
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.37 | 2.50 | 2.50 |
| 427.48 | 3.78 | 3.78 |
| 368.36 | 4.59 | 4.59 |
| 475.54 | 6.68 | 6.68 |
| 512.39 | 5.97 | 5.97 |
| 334.46 | 3.02 | 3.02 |
| 404.58 | 5.63 | 5.63 |
| 657.40 | 7.46 | 7.46 |
| 307.14 | 3.73 | 3.73 |
| 578.50 | 6.70 | 6.70 |
| 338.37 | 5.23 | 5.23 |
| 475.54 | 4.74 | 4.74 |
| 326.40 | 3.75 | 3.75 |