Basic Information
ID: ALA4153629
Type: Binding
Description: Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) at 33 uM preincubated for 15 mins followed by biotin tagged H3 peptide ( 1 to 23 residues) and [3H]-Ac-CoA addition and measured after 60 mins by radioactive acetylation assay
Format: BAO_0000019
Organism: Saccharomyces cerevisiae
Target: Histone acetyltransferase GCN5(ALA4669)
Document: ALA4152219
Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) at 33 uM preincubated for 15 mins followed by biotin tagged H3 peptide ( 1 to 23 residues) and [3H]-Ac-CoA addition and measured after 60 mins by radioactive acetylation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4153629
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.49 | 7.00 | 7.00 |
| 473.53 | 4.67 | 4.67 |
| 414.46 | 4.46 | 4.46 |
| 444.37 | 5.13 | 5.13 |
| 496.38 | 5.87 | 5.87 |