Basic Information
ID: ALA4154035
Type: Binding
Description: Binding affinity to N-terminal His6-tagged p53 DNA binding domain Y220C mutant (94 to 312 residues) (unknown origin) expressed in Escherichia coli C41 assessed as change in melting temperature at 250 uM by SYPRO orange dye based DSF analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4154035
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.91 | 2.30 | 2.30 |
| 385.16 | 3.05 | 3.05 |
| 405.19 | 4.15 | 4.15 |
| 389.15 | 1.86 | 1.86 |
| 470.00 | 2.51 | 2.51 |
| 457.29 | 3.94 | 3.94 |
| 373.15 | 2.88 | 2.88 |
| 401.20 | 3.66 | 3.66 |
| 451.01 | 2.86 | 2.86 |
| 387.17 | 3.27 | 3.27 |
| 423.18 | 4.29 | 4.29 |
| 403.24 | 3.99 | 3.99 |
| 537.14 | 2.78 | 2.78 |
| 435.22 | 4.16 | 4.16 |
| 449.24 | 4.11 | 4.11 |
| 441.01 | 2.88 | 2.88 |
| 525.13 | 2.68 | 2.68 |
| 441.14 | 3.82 | 3.82 |
| 468.08 | 3.45 | 3.45 |
| 401.20 | 3.52 | 3.52 |
| 468.03 | 2.75 | 2.75 |