Basic Information
ID: ALA4154343
Type: Binding
Description: Inhibition of calf thymus TOP1-mediated relaxation of supercoiled pBR322 DNA at 25 uM after 30 mins by agarose gel electrophoresis relative to camptothecin
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA4152240
Inhibition of calf thymus TOP1-mediated relaxation of supercoiled pBR322 DNA at 25 uM after 30 mins by agarose gel electrophoresis relative to camptothecin: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4154343
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.30 | 2.29 | 2.29 |
| 437.43 | 2.13 | 2.13 |
| 439.86 | 2.25 | 2.25 |
| 437.88 | 3.41 | 3.41 |
| 450.47 | 2.04 | 2.04 |
| 407.40 | 2.50 | 2.50 |
| 460.49 | 2.71 | 2.71 |
| 381.36 | 1.97 | 1.97 |
| 406.40 | 0.99 | 0.99 |
| 421.43 | 2.89 | 2.89 |
| 476.49 | 1.95 | 1.95 |
| 423.86 | 3.02 | 3.02 |
| 453.88 | 2.64 | 2.64 |
| 423.40 | 1.74 | 1.74 |
| 421.43 | 2.89 | 2.89 |
| 451.91 | 3.80 | 3.80 |
| 434.45 | 2.18 | 2.18 |
| 436.44 | 1.65 | 1.65 |
| 405.41 | 1.60 | 1.60 |
| 435.46 | 3.28 | 3.28 |
| 474.52 | 3.10 | 3.10 |
| 406.40 | 0.99 | 0.99 |
| 437.88 | 3.41 | 3.41 |
| 395.39 | 2.36 | 2.36 |