Basic Information
ID: ALA4154345
Type: Binding
Description: Inhibition of calf thymus TOP1-mediated relaxation of supercoiled pBR322 DNA at 125 uM after 30 mins by agarose gel electrophoresis relative to control
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA4152240
Inhibition of calf thymus TOP1-mediated relaxation of supercoiled pBR322 DNA at 125 uM after 30 mins by agarose gel electrophoresis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4154345
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 407.40 | 2.50 | 2.50 |
| 421.43 | 2.89 | 2.89 |
| 435.46 | 3.28 | 3.28 |