Basic Information
ID: ALA4154347
Type: Binding
Description: Poison activity at calf thymus TOP1 assessed as trapping of transient enzyme-DNA covalent complex by measuring ratio of nicked DNA at 25 uM using supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis (Rvb = 47%)
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4154347
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 407.40 | 2.50 | 2.50 |
| 421.43 | 2.89 | 2.89 |
| 435.46 | 3.28 | 3.28 |