Basic Information
ID: ALA4154377
Type: Functional
Description: Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated with cells followed by forskolin addition measured after 10 mins by luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Hydroxycarboxylic acid receptor 2(ALA3785)
Document: ALA4152241
Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated with cells followed by forskolin addition measured after 10 mins by luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4154377
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 123.11 | 0.78 | 0.78 |
| 440.46 | 4.69 | 4.69 |
| 430.89 | 5.82 | 5.82 |
| 454.48 | 4.95 | 4.95 |
| 405.89 | 4.62 | 4.62 |
| 426.47 | 4.97 | 4.97 |
| 410.47 | 5.48 | 5.48 |
| 402.48 | 5.03 | 5.03 |
| 385.47 | 4.27 | 4.27 |
| 378.38 | 3.08 | 3.08 |
| 410.47 | 5.27 | 5.27 |
| 392.41 | 3.47 | 3.47 |