Basic Information
ID: ALA4154412
Type: Binding
Description: Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by whole cell patch clamp electrophysiology method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4154412
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.22 | -1.86 | -1.86 |
| 337.42 | 4.77 | 4.77 |
| 388.86 | 5.05 | 5.05 |
| 290.33 | 2.93 | 2.93 |
| 324.77 | 3.58 | 3.58 |
| 262.70 | 2.23 | 2.23 |
| 326.31 | 3.21 | 3.21 |
| 500.73 | 5.34 | 5.34 |
| 304.35 | 3.24 | 3.24 |
| 450.67 | 4.19 | 4.19 |
| 414.90 | 5.56 | 5.56 |
| 373.24 | 4.55 | 4.55 |
| 399.25 | 3.70 | 3.70 |
| 383.80 | 3.80 | 3.80 |
| 288.31 | 2.98 | 2.98 |
| 495.66 | 4.10 | 4.10 |
| 338.80 | 3.89 | 3.89 |
| 318.38 | 3.55 | 3.55 |
| 322.34 | 3.38 | 3.38 |
| 417.69 | 4.66 | 4.66 |
| 302.34 | 3.29 | 3.29 |
| 383.25 | 4.00 | 4.00 |
| 417.69 | 4.66 | 4.66 |
| 308.32 | 3.07 | 3.07 |
| 428.25 | 3.91 | 3.91 |
| 433.31 | 5.15 | 5.15 |