Assay Report Card

Basic Information

ID: ALA4154413

Type: Binding

Description: Inhibition of human TRPM2 H995A mutant expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents at 30 uM treated extracellularly after 50 to 200 secs by whole cell patch clamp electrophysiology method

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
347.22-1.86-1.86
290.332.932.93
433.315.155.15