Basic Information
ID: ALA4154433
Type: Binding
Description: Inhibition of His-tagged BRD4 bromodomain-1 (unknown origin) expressed in Escherichia coli BL21(DE3) at 20 uM using SGRGK(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKVGG-K-Biotin as substrate preincubated for 15 mins followed by substrate addition measured after 10 mins by Alphascreen assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4154433
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.41 | 1.66 | 1.66 |
| 382.44 | 3.63 | 3.63 |
| 330.41 | 2.60 | 2.60 |
| 320.37 | 1.09 | 1.09 |
| 390.46 | 2.30 | 2.30 |
| 445.54 | 3.11 | 3.11 |
| 334.40 | 1.48 | 1.48 |
| 473.60 | 3.75 | 3.75 |
| 389.43 | 1.48 | 1.48 |
| 345.42 | 1.54 | 1.54 |
| 346.41 | 1.58 | 1.58 |
| 373.48 | 2.18 | 2.18 |
| 344.39 | 2.13 | 2.13 |
| 463.56 | 3.92 | 3.92 |
| 465.53 | 3.32 | 3.32 |
| 459.57 | 3.50 | 3.50 |
| 424.48 | 2.79 | 2.79 |
| 334.35 | 1.18 | 1.18 |
| 449.53 | 3.61 | 3.61 |
| 360.44 | 1.97 | 1.97 |
| 360.39 | 1.67 | 1.67 |
| 360.44 | 2.23 | 2.23 |
| 360.44 | 1.97 | 1.97 |
| 344.44 | 2.99 | 2.99 |
| 362.41 | 1.66 | 1.66 |
| 360.44 | 1.97 | 1.97 |
| 360.44 | 1.97 | 1.97 |
| 346.41 | 1.84 | 1.84 |
| 388.45 | 2.15 | 2.15 |
| 359.45 | 1.93 | 1.93 |
| 332.43 | 2.85 | 2.85 |
| 345.42 | 1.54 | 1.54 |
| 483.98 | 4.27 | 4.27 |
| 376.43 | 2.21 | 2.21 |
| 360.44 | 2.23 | 2.23 |
| 438.51 | 2.88 | 2.88 |
| 445.54 | 3.11 | 3.11 |
| 374.42 | 2.06 | 2.06 |
| 463.56 | 3.92 | 3.92 |
| 459.57 | 3.50 | 3.50 |
| 346.41 | 1.58 | 1.58 |
| 359.45 | 1.93 | 1.93 |
| 387.46 | 1.67 | 1.67 |
| 465.53 | 3.32 | 3.32 |
| 459.57 | 3.50 | 3.50 |
| 348.38 | 1.57 | 1.57 |
| 316.38 | 2.21 | 2.21 |
| 388.45 | 0.96 | 0.96 |
| 359.45 | 1.93 | 1.93 |
| 346.41 | 1.58 | 1.58 |
| 344.44 | 2.99 | 2.99 |