Basic Information
ID: ALA4154604
Type: Binding
Description: Inhibition of AIP-stimulated quorum sensing system AgrC activation in Staphylococcus aureus RN10829 harboring P3:blaZ fusion assessed as reduction in beta-lactamse activity at 5 ug/ml preincubated with organism followed by AIP addition measured after 45 mins by nitrocefin hydrolysis assay
Organism: Staphylococcus aureus
Strain: RN10829
Activity Charts
Bioactivity
Activity Types for Assay ALA4154604
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 656.87 | 2.26 | 2.26 |
| 566.74 | 0.64 | 0.64 |
| 681.88 | 2.35 | 2.35 |
| 642.84 | 1.87 | 1.87 |
| 676.86 | 2.06 | 2.06 |
| 642.84 | 1.87 | 1.87 |
| 600.76 | 0.84 | 0.84 |
| 670.90 | 2.65 | 2.65 |
| 642.84 | 1.87 | 1.87 |
| 743.86 | -2.74 | -2.74 |
| 656.87 | 2.26 | 2.26 |
| 572.71 | -0.09 | -0.09 |
| 684.92 | 2.89 | 2.89 |
| 628.82 | 1.48 | 1.48 |
| 684.92 | 3.04 | 3.04 |
| 642.84 | 1.87 | 1.87 |
| 656.87 | 2.26 | 2.26 |
| 642.84 | 1.87 | 1.87 |
| 692.90 | 3.02 | 3.02 |
| 684.92 | 3.04 | 3.04 |
| 712.98 | 3.82 | 3.82 |
| 690.84 | -0.43 | -0.43 |
| 600.76 | 0.84 | 0.84 |
| 656.87 | 2.26 | 2.26 |
| 656.87 | 2.26 | 2.26 |
| 628.81 | 1.48 | 1.48 |
| 642.84 | 1.87 | 1.87 |