Basic Information
ID: ALA4154605
Type: Binding
Description: Inhibition of AIP-stimulated quorum sensing system AgrC activation in Staphylococcus aureus RN10829 harboring P3:blaZ fusion assessed as reduction in beta-lactamse activity preincubated with organism followed by AIP addition measured after 45 mins by nitrocefin hydrolysis assay
Organism: Staphylococcus aureus
Strain: RN10829
Activity Charts
Bioactivity
Activity Types for Assay ALA4154605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 656.87 | 2.26 | 2.26 |
| 676.86 | 2.06 | 2.06 |
| 600.76 | 0.84 | 0.84 |
| 642.84 | 1.87 | 1.87 |
| 628.82 | 1.48 | 1.48 |
| 642.84 | 1.87 | 1.87 |
| 656.87 | 2.26 | 2.26 |
| 656.87 | 2.26 | 2.26 |