Basic Information
ID: ALA4154870
Type: Binding
Description: Inhibition of His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4154870
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 509.05 | 5.48 | 5.48 |
| 326.40 | 4.24 | 4.24 |
| 334.38 | 3.90 | 3.90 |
| 300.36 | 3.70 | 3.70 |
| 312.37 | 3.48 | 3.48 |
| 368.82 | 4.55 | 4.55 |
| 338.34 | 4.17 | 4.17 |
| 383.45 | 2.94 | 2.94 |
| 298.34 | 3.46 | 3.46 |
| 320.35 | 4.03 | 4.03 |
| 286.33 | 3.31 | 3.31 |
| 370.41 | 3.03 | 3.03 |
| 388.35 | 5.05 | 5.05 |
| 389.24 | 5.34 | 5.34 |
| 286.33 | 3.46 | 3.46 |
| 354.79 | 4.68 | 4.68 |
| 340.42 | 4.63 | 4.63 |
| 300.36 | 3.70 | 3.70 |
| 389.24 | 5.34 | 5.34 |
| 326.40 | 3.87 | 3.87 |
| 334.38 | 3.90 | 3.90 |
| 338.34 | 4.17 | 4.17 |
| 369.47 | 3.41 | 3.41 |
| 312.37 | 3.85 | 3.85 |
| 298.34 | 3.46 | 3.46 |
| 300.36 | 3.70 | 3.70 |
| 356.38 | 2.94 | 2.94 |
| 388.35 | 5.05 | 5.05 |
| 354.79 | 4.68 | 4.68 |
| 318.40 | 3.41 | 3.41 |
| 298.34 | 3.46 | 3.46 |
| 300.36 | 3.85 | 3.85 |
| 354.79 | 4.68 | 4.68 |
| 411.50 | 3.18 | 3.18 |