Basic Information
ID: ALA4154873
Type: Binding
Description: Binding affinity to His6-tagged human BRD2 bromodomain-1 (K77 to N194 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4154873
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 338.34 | 4.17 | 4.17 |
| 320.35 | 4.03 | 4.03 |
| 300.36 | 3.70 | 3.70 |
| 326.40 | 3.87 | 3.87 |
| 298.34 | 3.46 | 3.46 |
| 411.50 | 3.18 | 3.18 |