Basic Information
ID: ALA4154877
Type: Binding
Description: Binding affinity to His6-tagged human BRD4 bromodomain-2 expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4152259
Binding affinity to His6-tagged human BRD4 bromodomain-2 expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4154877
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 338.34 | 4.17 | 4.17 |
| 320.35 | 4.03 | 4.03 |
| 300.36 | 3.70 | 3.70 |
| 326.40 | 3.87 | 3.87 |
| 298.34 | 3.46 | 3.46 |
| 411.50 | 3.18 | 3.18 |