Basic Information
ID: ALA4155117
Type: Binding
Description: Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4155117
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 428.27 | 3.48 | 3.48 |
| 517.17 | 3.78 | 3.78 |
| 493.78 | 2.51 | 2.51 |
| 479.75 | 2.42 | 2.42 |
| 442.30 | 3.87 | 3.87 |
| 483.31 | 2.39 | 2.39 |
| 543.40 | 3.99 | 3.99 |
| 551.19 | 4.19 | 4.19 |
| 482.32 | 3.84 | 3.84 |
| 503.15 | 3.39 | 3.39 |
| 583.43 | 3.95 | 3.95 |
| 456.33 | 2.78 | 2.78 |
| 442.30 | 3.87 | 3.87 |
| 630.72 | 3.56 | 3.56 |
| 428.27 | 3.48 | 3.48 |