Basic Information
ID: ALA4155118
Type: Binding
Description: Inhibition of Escherichia coli C-terminal His6-tagged topoisomerase-4 expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4155118
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 479.75 | 2.42 | 2.42 |
| 442.30 | 3.87 | 3.87 |
| 483.31 | 2.39 | 2.39 |
| 482.32 | 3.84 | 3.84 |
| 442.30 | 3.87 | 3.87 |
| 428.27 | 3.48 | 3.48 |